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更新时间:2022-12-28
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Association of Insufficient Sleep With Respiratory Infection Among Adults in the United States.聽JAMA Intern. Med.聽2016;176:850鈥?52. [2]5 Prather, A. A., Janicki-Deverts,D., Hall, M. H. & Cohen, S. Behaviorally Assessed Sleep and Susceptibility to the Common Cold.Sleep38, 1353-1359, (2015). [3]Rizza S., Coppeta L., Grelli S., Ferrazza G., Chiocchi M., Vanni G., Bonomo O.C., Bellia A., Andreoni M., Magrini A., et al. High Body Mass Index and Night Shift Work Are Associated with COVID-19 in Health Care Workers.聽J. Endocrinol. Investig.聽2021;44:1097鈥?101. [4]https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8954484/ [5]Huang B., Niu Y., Zhao W., Bao P., Li D. Reduced Sleep in the Week Prior to Diagnosis of COVID-19 Is Associated with the Severity of COVID-19.聽Nat. Sci. Sleep.聽2020; [6]Dimitrov, S.et al.G伪s-coupled receptor聽signaling and sleep regulate integrin activation of human antigen-specific T聽cells.Journal of Experimental Medicine216, 517-526,聽锛?019锛?/p> [7]Lange, T., Perras, B., Fehm, H. L.& Born, J. Sleep enhances the human antibody response to聽hepatitis聽Avaccination.Psychosom Med65,聽831-835, (2003). [8]Lange, T., Dimitrov, S.,Bollinger, T., Diekelmann, S. & Born, J. Sleep after vaccination boosts immunological memory.J Immunol187, 283-290, (2011). [9]Spiegel, K., Sheridan, J. F. &Van Cauter, E. Effect of聽sleep deprivation聽on response to immunization.Jama288, 1471-1472, (2002). [10]Cappuccio, F. P., D'Elia, L.,Strazzullo, P. & Miller, M. A. Sleep duration and all-cause mortality: a systematic review and聽meta-analysis聽of prospective聽studies. Sleep 33, 585-592, (2010). [11]https://pubmed.ncbi.nlm.nih.gov/35174134/ [12]www.sleepfoundation.org [13]https://www.ifm.org/news-insights/good-sleep-hygiene-may-help-protect-infectious-diseases/ [14]https://www.sleepfoundation.org/nutrition/alcohol-and-sleep [15]https://sleepeducation.org/sleep-caffeine/ 浣滆€咃細绔炰竴 缂栬緫锛氭潕灏忚懙 棰樺浘鏉ユ簮锛氬浘铏垱鎰?/p> 涓€涓狝I 杈涜嫤浜嗗疄楠屼腑鐫′笉濂借鐨勫織鎰胯€呫€?/p> |